“We started using these 4 years ago. One dog had considerable plaque buildup which then was gone in a few weeks. These were not available during much of the pandemic, and now are more expensive than before. We had to try other “dental chews,” but none worked as well. Do Not Doubt – These get rid of plaque and keep it away. Our two 25 pound dogs each get 1/2 daily after their lunch. They like them so much that they sometimes stop eating their lunch and stand by the pantry where these are stored.”